As native South Carolinian’s, we set out here to provide a reference for each operating destination vineyard and winery in the state. Our research has uncovered 18 operating wineries and 2 cideries and 2 Meaderies.
Majority of South Carolina offers a challenge to grow the common European vinifera varieties, yet some offerings can be found. Many unique offerings of muscadine, native, French-American hybrids, and some excellent fruit wines, meads, and hard ciders are certainly produced.
We encourage as you travel into and through South Carolina, stop and enjoy some of the excellent wines and destination vineyards in the Palmetto state. We think you’ll be pleasantly surprised. If you’re local, you will find your local winery a great place to spend a relaxing day with family and/or friends.
First we’ll take a look at the operating wineries with estate vineyards.
1. CityScape Winery – Pelzer (Greenville County)
A small rural boutique winery south of Greenville, operating since 2007 ish. The current owners bought the winery just five years ago. Growing Carlos, Noble, Spanish Black, and Blanc du Bois on site. Josh and Deb, owners and winemakers, also import grapes from other prominent wine regions. The wineries mascot, is the adorable Pinot the Pig. You can often find him tethered outside the tasting room sporting his super hero costume.
CityScape will be opening a brand new 10,000 square foot tasting room in early 2022.
Location: 589 Dunklin Bridge Rd.
Recommendation: Müller Two-Goats (Müller-Thurgau)
2. Victoria Valley Vineyards – Cleveland
Mountain vineyard and winery styled after a French chateau, offering a bistro with enchanting views of the mountains overlooking their vineyards. Growing several varieties of vinifera wines, which can be enjoyed with lunch from their gorgeous open air terrace.
Location: 1360 S. Saluda Rd.
Recommendation: White Merlot
3. Enoree River Winery – Newberry
Open 11 years now and still going strong, this vineyard and winery sits just off Interstate 26 about 30 miles Northwest of Columbia. Growing Carlos and Noble, plus Herbemont and Lenoir on site, offers several handcrafted blends and fruit wines along with several seasonal wines available. The winery offers a spacious tasting room and a beautiful deck overlooking the vineyards, perfect for relaxing with a bottle of good wine.
Location: 1650 Dusty Rd.
Recommendation: Seasonal Fruit Wines
4. Mercer House Estate Winery – Lexington
The Winery at Mercer House is a rural craft estate winery. Many muscadine and blends are offered, along with a few very unique wines. Try the very unique Blueberry Jalapeño wine.
Location: 397 Walter Rawl Rd.
Recommendation: Apple Pie
5. Deep Water Vineyard -Wadmalar Island
Charleston area’s only Vineyard and Winery, originally Irvin – House Vineyard. Nestled among the live oaks just outside of Charleston.
Location: 6775 Bears Bluff Rd.
Recommendation: Magnolia
6. Wellborn Winery – Travelers Rest
This Winery in the Woods is growing French-American Hybrid varietals and sourcing other fruit from local South Carolina Farms. A Small tasting room is complimented with a beautiful scenic outdoor patio and seating spread about the yard. A small AirBnB house overlooking the vineyards is available for overnight accommodations.
Location: 254 Mush Creek Road
Recommendation: Rustic Red
Not a destination winery, a working vineyard which doesn’t support a tasting room. Their wines are sold at local farmers markets.
Location: Pee Dee Farmers Market, Florence
Recommendation: Southern Sunrise
International award winning small winery focusing on fruit and berry wines produced from estate grown and local farm sourced fruit. Lazy Bear is also producing several award winning meads.
Location: 644 Hester Store Rd.
Recommendation: Peach Berry Medley or Plum
9. Cartersville Country Winery – Timmonsville
Working Vineyard and Winery and wedding venue located just off the intersection of Interstate 26 and Interstate 95 near Florence. Growing muscadine with twenty acres under vine and also producing real fruit wines. Overnight accommodations and full camper hookups available. No joke, winemaker is named Carlos Noble.
Location: 571 Lamar Hwy.
Family owned Muscadine vineyard and winery since 2004. Open only each Saturday Bowman wines can also be purchased at their farm store in Augusta Hwy just outside of Walterboro.
Note: La Belle Amie Vineyard and Winery – Little River
Technically not a winery though a working vineyard, tasting room, and gift shop serving the Grand Strand area. The vineyard is popular among the millions of visitors each year to the Myrtle Beach and surrounding Grand Strand area.
Location: 1120 St. Joseph Rd.
Recommendation: Cabana Boy “Just Peachy”
The wineries listed below are operating without support of their own vineyard. Each is unique in it’s own way and provide a destination to relax and enjoy some good wine.
11. Cats Paw Winery – Rock Hill
Small craft winery nestled on farm land just Southeast of Charlotte.
Location: 1567 Fayrene Rd., Rock Hill
Recommendation: Strawberry Sensation
12. Old Rock Quarry Winery -Enoree
Small rural craft winery in Spartanburg county located just off Interstate 26. Offering a diverse selection of semi-dry and sweet fruit infused wines. Described to be reminiscent of visiting your neighbors, whom just happen to make good homemade wine.
Location: 629 Old Rock Quarry Rd., Enoree
Recommendation: Snap Apple Sassy
The following three are urban wineries in the Myrtle Beach Grand Strand area. All three are in high tourist shopping venues.
13. Carolina Vineyards Winery – Myrtle Beach
Location: Barefoot Landing, N. Myrtle
Recommendation: Bare-Foot Blush
14. Boardwalk Winery – Myrtle Beach
Location: Broadway at the Beach
Recommendation: Wine Slushie
Coastal Carolina Winery operates tasting rooms in Myrtle Beach and Pawley’s Island, however the wine is produced in North Carolina.
One urban winery can be found on Hilton Head Island.
15. Island Winery – Hilton Head
Location: 12A Cardinal Rd.
Recommendation: Southern Passion
One urban winery can be found in Greenville.
Urban winery about one mile from downtown near the downtown airport. Really nice outdoor patio for enjoying a nice weather day.
Location: 301 Airport Rd.
Recommendation: Delight
South Carolina‘s Newest Winery
17. South Bend Winery – Greenwood
Nestled on 6 acres of old farm land on the South side of Greenwood. The tasting is a remodeled old farm house. The winery has plenty of of outdoor space and a nice fire pit out back.
A few others of mention.
18. Silver Dew Winery is found on Dafuskie Island near Hilton Head. A very historic and significant winery in South Carolina history.
You may also find of interest…,
Duplin Winery operates a tasting room in North Myrtle Beach, however Duplin is a North Carolina based Vineyard and Winery.
Cideries.
Windy Hill Apple Orchard and Cidery in York is alway busy during the fall Apple harvest season.
Fat Ass Heifer Cidery operates in Campobello, opening each Saturday for tastings. You know you want the t-shirt!
Location: 10125 New Cut Road.
Ships Wheel Hard Cider operates tasting room in North Charleston. Ciders are currently produced in this location.
Location: North Charleston.
Meaderies.
Wandering Bard Meadery just recently opened a taproom in the Greenville’s Hampton Station .
Bee Town Mead and Cider is located in Bluffton near Hilton Head Island. 
Eagle Mountain Vineyards Vineyard and boutique winery in Travelers Rest. Eagle Mountain does not produce wine in South Carolina but proudly offers a California wine experience.
As always, use the VinoWine app for details and directions.
Updated 12/31/2021
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